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About the DTU

The Diabetes Trials Unit (DTU) is a fully registered UKCRC Clinical Trials Unit, specialising in performing national and multinational clinical trials related to diabetes.

Our trials, which are all conducted to Good Clinical Practice (GCP) standards, range from proof of concept and efficacy studies (Phase IIA/B) to Phase III and Phase IV randomised multi-centre and international controlled trials.

Our current multinational clinical trials include ACE and EXSCEL.

We also undertake major modelling and statistical programmes to fully utilise the data available from our many studies, with a particular emphasis on modelling diabetes and cardiovascular disease processes.

We work in partnership with, collaborate or receive funding from the NHS, the National Institute for Health Research (NIHR), National Institute of Health (NIH), Medical Research Council (MRC), British Heart Foundation (BHF), Diabetes UK (DUK), academic institutions and industry.

The DTU in context

The DTU was founded in 1985 by Professor Rury Holman, who is the Director of the unit. We are a founder member of the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) and are based within the OCDEM building. OCDEM is a pioneering centre combining clinical care, research and education in diabetes, endocrine and metabolic diseases.

DTU and OCDEM are part of the University of Oxford’s newly-formed Radcliffe Department of Medicine. DTU’s Translational Research Group is part of the Oxford Biomedical Research Centre, funded by the UK National Institute for Health Research (NIHR).