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TECOS study launched

News Image The Trial to Evaluate Cardiovascular Outcomes after Treatment with Sitagliptin (TECOS) clinical trial launched.


Prevalence of GCK mutations in fasting hyperglycaemia

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AFORRD results published online

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UKCRC Registered Clinical Trials Units website launched

News Image A new comprehensive online resource listing national expertise in the design and conduct of clinical trials is launched today. The UKCRC Registered Clinical Trials Units website provides, for the first time, centralised information on Clinical Trials Units (CTUs) in the UK with expertise in centrally coordinating multicentre clinical trials from design and development, through to data management, and final analysis....

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Ethics approval received for the Acarbose Cardiovascular Evaluation (ACE) trial

News Image The ACE trial has received ethics approval from the Oxford Tropical Research Ethics Committee (OXTREC). This independent body, based at Oxford University, specializes in the review of trials which do not recruit in Europe....

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NAVIGATOR Design Paper published

News Image Prevention of diabetes and cardiovascular disease in patients with impaired glucose tolerance: Rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial Rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial

Robert M. Califf, Mitradev Boolell, Steven M....

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UKPDS shows glucose control and metformin legacy effects

News Image The UKPDS 10-year post-trial monitoring results were presented at the 44th EASD meeting in Rome on Wednesday 10th September 2008.

They showed continuing benefit of earlier improved glucose control, with emergent significant risk reductions for myocardial infarction and all-cause mortality, despite loss of within trial blood glucose and antihyperglyaemic therapy differences - a legacy effect....

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30-year UKPDS results

News Image The results of the UKPDS post-trial monitoring follow-up are being be presented at the 2008 EASD.
See link below for more details....

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Selecting components for composite endpoints

News Image Determining the most appropriate components for a composite clinical trial outcome

M. Angelyn Bethel, Rury Holman, Steven M....

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Diabetic Medicine supplement with eleven UKPDS review articles

News Image The August 2008 issue of Diabetic Medicine includes a UKPDS Supplement, edited by Rury Holman and Peter Watkins. This Supplement contains eleven specially commissioned articles that review many of the contributions that have been made by UKPDS in different areas of interest....

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DTU to run sitagliptin outcome trial with DCRI

Merck has signed a letter of intent with Oxford Diabetes Trial Unit and Duke Clinical Research Institute to design and conduct a clinical cardiovascular outcomes study with sitagliptin (JANUVIA)


Acarbose Cardiovascular Evaluation (ACE) trial launched

News Image The Acarbose Cardiovascular Evaluation (ACE) trial was launched on Friday 11th April 2008 at the 10th South China International Congress of Cardiology in Guangzhou, China. ACE is a multi-centre clinical outcome trial coordinated by the Diabetes Trial Unit and run in China with the guidance of an international Steering Committee of diabetologists and cardiologists....

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Banting Memorial Lecture Awarded to Rury Holman

News Image The Diabetes UK (DUK) Banting Memorial Lecture is the highest award bestowed by Diabetes UK. The lecture is awarded to a person internationally recognised for their eminence in the field of diabetes.


OCDEM and YDF present ... Diabetes State of the Art Course

30th and 31st October 2008

The Young Diabetologists Forum (YDF) has joined forces with the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) to develop an educational programme for Year 4 and 5 SpRs.

This year's programme will be held over two days at the end of October and will be chaired by Prof Sir George Alberti and Prof Rury Holman....

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ClinicaL Decisions. Management of Type 2 Diabetes

News Image Type 2 Diabetes
This interactive Journal feature presents the case of a 55-year-old woman with type 2 diabetes, obesity, and hypertension, together with three possible treatment options and expert opinion on each. Vote on the option you would recommend, and submit a comment about your clinical decision....

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