Trial Evaluating Cardiovascular Outcomes With Sitagliptin

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TECOS is a double-blind randomized, placebo controlled, multi-national trial in patients with Type 2 Diabetes coordinated by the Duke Clinical Research Institute (DCRI) and the University of Oxford Diabetes Trial Unit (DTU).

It is being conducted in around 40 countries, across Australasia, Asia, Europe, North America, South America, India and South Africa, and commenced in 2008. TECOS aims to compare the impact of adding sitagliptin as part of usual care versus usual care without sitagliptin on cardiovascular outcomes. 14,000 patients will be followed for a minimum of 3 years with the results expected in 2015.

Co-Chair: Professor Robert Califf (Duke University, US)
Co-Chair: Professor Rury Holman (The University of Oxford, UK)
Clinical Lead (Durham, USA): Dr Jennifer Green
Clinical Lead (Oxford, UK): Dr Angelyn Bethel
Project Manager (Durham, USA): Tyrus Rorick
Project Manager (Oxford, UK): Jo Milton

Clinical trials.gov identifier: NCT00790205

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2012

April

TECOS trial members gather for annual European meeting

TECOS is funded by Merck in an academic collaboration with the Duke Clinical Research Institute and the Diabetes Trials Unit.