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The Early Diabetes Intervention Trial (EDIT) was a six-year, prospective, randomised, double-blind, placebo-controlled study in subjects thought to be at increased risk of developing diabetes, and who had two consecutive fasting plasma glucose levels in the range 5.5 to 7.7 mmol/L. The primary aim of the trial was to determine whether deterioration in glycaemic tolerance towards diabetes could be delayed or prevented using an alpha-glucosidase inhibitor (acarbose) or a biguanide (metformin). The trial results were presented at the 2003 Diabetes UK meeting.

• Principal Investigator: Professor Rury Holman
• Study Manager: Ms Lynne Tucker
  
  
• ISRCTN number: 96631607
  

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EDIT Office, Diabetes Trials Unit, OCDEM, Churchill Hospital, Old Road, Headington, Oxford, OX3 7LJ, UK
Tel: +44 (0)1865 857243     Fax: +44 (0)1865 857256    Email: dtu@dtu.ox.ac.uk

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