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The Diabetes Trials Unit (DTU), founded in 1985 by Professor Rury Holman, specialises in performing diabetes-related national and multinational mega trials in partnership with the NHS, NIH, MRC, BHF, DUK, academic institutions and industry. The DTU also undertakes major modelling and statistical programmes to utilise fully the data available from its many studies, with a particular emphasis on modelling diabetes and cardiovascular disease processes. Current studies include 4-T, ACE, TECOS and UKPDS~Post Study Monitoring. [More...]

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TRG Research Bulletin 15 - 2014

01-Aug-2014
News Image The third edition of the 2014 TRG newsletter is now available...
[Full article]

2014 Oxford BRC Open Day

26-May-2014
News Image The 2014 Oxford Biomedical Research Centre annual open day was held on Monday May 19, with teams demonstrating the latest technology and techniques tackling conditions such as cancer, dementia, arthritis and diabetes...
[Full article]

DTU Clinician gives invited memorial lecture

14-May-2014
News Image On Friday 9 May, DTU Clinical Researcher Dr Matthew Wintle gave the invited Bill Williams Memorial Lecture at the Spring Meeting of the Society of Physicians in Wales...
[Full article]

DTU Clinician attains highest level of membership of the Royal College of Physicians

13-May-2014
Congratulations to DTU Senior Clinical Researcher Dr Michael Theodorakis, who has become a Fellow of the Royal College of Physicians (FRCP), the highest level of membership awarded by the College...
[Full article]

TRG Research Bulletin 14 - 2014

22-Apr-2014
News Image The second edition of the 2014 TRG newsletter is now available...
[Full article]

Researchers believe heart failure risks of glucose-lowering drugs are being overlooked in clinical trials

13-Mar-2014
News Image In a personal view article published online today in the journal The Lancet Diabetes & Endocrinology, researchers are calling for the systematic evaluation of heart failure to be included routinely in clinical outcome trials of glucose-lowering drugs...
[Full article]

DTU Clinician wins Oxford College scholarship

07-Mar-2014
News Image Congratulations to our senior clinical researcher Dr Jyothis George, who has been appointed as a Robert Turner Research Associate until December 2014 at Green Templeton College (GTC), University of Oxford...
[Full article]

DTU Director gives special invited lecture in Taipei

05-Mar-2014
News Image Professor Rury Holman gave a special invited lecture at the 35th annual meeting of the Diabetes Association and the Endocrinology Society of the Republic Of China (Taiwan) on Sunday 2nd March 2014...
[Full article]

DTU appoints new Clinical Researcher

05-Mar-2014
News Image We are delighted to announce that Dr Matthew Wintle has joined the Diabetes Trials Unit (DTU) as a Clinical Researcher...
[Full article]

New software version of HOMA2 model released

20-Feb-2014
News Image Today we release the latest software version of our HOMA2 Calculator, which enables researchers to quickly assess the level of insulin resistance and how well beta cells are working in people with diabetes...
[Full article]

OCDEM event brings together Oxford researchers and industry to encourage new research collaborations

06-Feb-2014
News Image On 23rd January 2014, DTU Director Professor Rury Holman led an OCDEM Industry Networking Event to showcase translational diabetes research in Oxford and bring leading academics and R&D companies together to foster new collaborations...
[Full article]

DTU takes part in 2014's OCDEM Day

27-Jan-2014
DTU Director Prof Rury Holman gave the plenary talk at this year's OCDEM day, held on Friday 24th January...
[Full article]

TRG Research Bulletin 13 - 2014

21-Jan-2014
News Image The first edition of the 2014 TRG newsletter is now available...
[Full article]

DTU launches new website

23-Dec-2013
News Image The DTU has today launched it's new website...
[Full article]

DTU Director gives plenary lecture at the IDF World Diabetes Congress

09-Dec-2013
Professor Rury Holman gave an invited plenary lecture at the International Diabetes Federation (IDF) 2013 World Diabetes Congress in Melbourne, Australia on 4th December...
[Full article]

TRG Research Bulletin 12 - 2013

29-Oct-2013
News Image The fourth edition of the 2013 TRG newsletter is now available...
[Full article]

Dr George wins 2013 Myre Sim Award

25-Oct-2013
News Image The Myre Sim Award is made biennially by The Royal College of Physicians of Edinburgh...
[Full article]

DTU appoints new Senior Clinical Researcher

31-Jul-2013
News Image We are delighted to announce that Dr Jyothis George has joined the Diabetes Trials Unit (DTU) as a Senior Clinical Researcher...
[Full article]

TRG Research Bulletin 11 - 2013

26-Jul-2013
News Image The third edition of the 2013 TRG newsletter is now available...
[Full article]

New version of the UKPDS Outcomes Model published

22-Jun-2013
News Image The new UKPDS-OM2 has significant advantages over the existing model, as it captures more outcomes, is based on longer follow-up data, and more comprehensively captures the progression of diabetes...
[Full article]

Prof Holman appointed as Visiting Professor to Capital Medical University, Beijing.

28-May-2013
News Image On 27th May 2013 Professor Holman gave a talk entitled "New Understanding of the UKPDS 'Legacy Effect'" at Tongren Hospital, Beijing, China following his appointment in December 2012 as Visiting Professor to Capital Medical University...
[Full article]

DTU Director gives Special Lecture at 56th Annual JDS Meeting

17-May-2013
News Image Prof Holman gave one of the two Special Lectures at this year's Japanese Diabetes Society meeting in Kumamoto, Japan on May 17th...
[Full article]

TRG Research Bulletin 10 - 2013

01-May-2013
News Image The second edition of the 2013 TRG newsletter is now available...
[Full article]

The Global Reach of TECOS

26-Mar-2013
News Image 2012 was an exciting year for TECOS that saw the close of recruitment following randomisation of over 14,700 participants...
[Full article]

New study suggests one in six people with newly-diagnosed diabetes may have had a silent heart attack in the past

01-Feb-2013
News Image Research published online this week by DTU and Australian researchers has found that one in six people with newly-diagnosed type 2 diabetes may have experienced a silent myocardial infarction (SMI) - a heart attack without chest pain or symptoms - in the past...
[Full article]

TRG Research Bulletin - Spring 2013

30-Jan-2013
News Image The spring edition of the TRG newsletter is now available...
[Full article]

New DTU study finds that screening for diabetes could be done at home

15-Jan-2013
News Image Research published online today led by DTU researchers has found that people may be able to test themselves for diabetes in the comfort of their own home, using a novel electronic screening device...
[Full article]

DTU now part of Oxford's newly-created Radcliffe Department of Medicine

18-Dec-2012
News Image The Diabetes Trials Unit (DTU) has joined the Radcliffe Department of Medicine, a large new multidisciplinary department within the Medical Sciences Division of the University of Oxford...
[Full article]

DTU Director gives invited talks in Chile and the US

29-Nov-2012
News Image November has seen Professor Rury Holman give several invited talks at global meetings in Chile and the USA...
[Full article]

New DTU video encourages people to participate in diabetes trials

14-Nov-2012
News Image A new video from the Diabetes Trials Unit (DTU) at the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) is being launched today, on World Diabetes Day...
[Full article]

TRG Research Bulletin - Autumn 2012

07-Nov-2012
News Image The autumn edition of the TRG newsletter is now available...
[Full article]

Oxford University ranked top in the world for medicine

04-Oct-2012
News Image Oxford University has retained its position as best in the world for medicine, in the Times Higher Education World University Rankings...
[Full article]

First CIDE Visiting Professor

22-Sep-2012
News Image DTU Director Professor Rury Holman was elected as the first China Initiative for Diabetes Excellence (CIDE) program Visiting Professor on 21st September 2012, and gave four invited talks at their two-day meeting in Hangzhou, China...
[Full article]

DTU's Full UKCRC Clinical Trials Unit Registration has been renewed

29-Aug-2012
News Image We are delighted to announce that the DTU's full registration by the UK Clinical Research Collaboration (UKCRC) has been renewed, which enables us to continue to work as a UKCRC Clinical Trials Unit...
[Full article]

TRG Research Bulletin - Summer 2012

27-Aug-2012
News Image The summer edition of the TRG newsletter is now available...
[Full article]

Study suggests diabetes drug metformin does not protect against cancer

21-Aug-2012
News Image Research published online this month led by researchers at the University of Oxford, including DTU, suggests that the diabetes drug metformin does not prevent people from developing cancer...
[Full article]

Successful Finishing School for Specialist Registrars held in Oxford

11-Jul-2012
The eighth OCDEM / Young Diabetologists' Forum (YDF) Finishing School was held at Eynsham Hall, Oxford on 21 and 22 June, chaired by Professors Rury Holman and Edwin Gale...
[Full article]

DTU appoints new Senior Clinical Researcher

11-Jul-2012
News Image We are delighted to announce that Dr Michael Theodorakis joined the Diabetes Trials Unit (DTU) as a Senior Clinical Researcher on 1st July...
[Full article]

TECOS celebrates enrolment milestone at the ADA

28-Jun-2012
News Image We are delighted to announce that more than 14,000 patients have now been recruited to the Trial Evaluating Cardiovascular Outcomes With Sitagliptin (TECOS) trial...
[Full article]

DTU staff attend ADA conference in the States

13-Jun-2012
News Image Several DTU staff presented their work at the American Diabetes Association (ADA) conference in Philadelphia, USA, this week...
[Full article]

Prof Holman speaks about ACE trial at ADA conference

13-Jun-2012
News Image DTU Director Professor Rury Holman gave an invited talk at the first joint China Medical Tribune and American Diabetes Association (ADA) symposium - 'A Perspective on "Metabetes" from China' - in Philadelphia, USA on Saturday 9th June...
[Full article]

Members of DTU accompany University's Vice-Chancellor on China visit

23-May-2012
News Image DTU Director Professor Rury Holman, Head of Development Joanne Keenan and Head of Clinical Research Zoe Doran have accompanied Oxford's Vice-Chancellor Professor Andrew Hamilton and researchers from the Nuffield Department of Medicine (NDM) on a visit to China...
[Full article]

Local press helps DTU seek volunteers for aspirin trial

18-May-2012
News Image A clinical trial run by DTU's Translational Research Group (TRG) has featured in the local media in the hope that it encourages people to take part...
[Full article]

Prof Holman gives opening speech at Chinese Diabetes meeting

15-May-2012
News Image Professor Rury Holman gave the opening keynote speech at the 4th annual Asian-Pacific Bayer Chinese Diabetes (ABCD) meeting in Chengdu, China on Saturday 12th May...
[Full article]

DTU Director joins prestigious Academy of Medical Sciences

10-May-2012
News Image We are delighted to announce that Professor Rury Holman has been elected as a Fellow of the prestigious Academy of Medical Sciences, for his outstanding contribution to medical science...
[Full article]

DTU Director speaks at largest ever European Endocrinology conference

07-May-2012
News Image Professor Rury Holman was invited to speak at the 15th International Congress of Endocrinology (ICE), held in conjunction with the 14th European Congress of Endocrinology, on Sunday 6th May...
[Full article]

Professor Holman gives talk at ESH meeting in London

29-Apr-2012
News Image Professor Rury Holman gave an invited talk at the 22nd annual European Meeting on Hypertension and Cardiovascular Protection on Sunday 29th April...
[Full article]

DTU Clinician wins Oxford College scholarship

03-Apr-2012
News Image Congratulations to our senior clinical researcher Dr Harald Sourij, who has been appointed the Robert Turner Research Associate for one year at Green Templeton College (GTC), University of Oxford...
[Full article]

More evidence that gene variations influence metformin response

30-Mar-2012
News Image Together with others, DTU researchers have confirmed that a variation in a gene called ATM could help to explain why some people have a better response to a first-line drug for type 2 diabetes called metformin...
[Full article]

DTU Director invited to speak at Abu Dhabi conference

26-Mar-2012
News Image Professor Rury Holman gave a keynote talk at the Second Annual PharmaCoEconomics Middle East Forum in Abu Dhabi on 23rd March...
[Full article]

Successful 2012 Oxford Biomedical Research Centre Open Day

15-Mar-2012
News Image Several groups within the Oxford Biomedical Research Centre (BRC) Diabetes Theme took part in this year's public open day which was held on the 14th March in the Churchill Hospital...
[Full article]

DTU appoints a new Deputy Director

29-Feb-2012
News Image We are delighted to announce that Dr Angelyn Bethel will become the new Deputy Director of the Diabetes Trials Unit (DTU) from 5th March...
[Full article]

Professor Holman speaks at tenth annual NNDU meeting in China

12-Feb-2012
News Image Professor Rury Holman gave an invited keynote talk at the annual Novo Nordisk Diabetes Update (NNDU) in Tianjin, China on Sunday 12th February...
[Full article]

Women develop diabetes at higher BMIs than men

11-Jan-2012
News Image In an analysis of the British Regional Heart Study and the British Women´s Heart Health Study, Wannamethee and colleagues report that women develop diabetes at higher BMIs than men...
[Full article]

Why Medicine Needs Better Trials and Reporting

04-Jan-2012
News Image In an age of media saturation and information overload, it is becoming more difficult to discern real health and safety signals from background noise...
[Full article]

How FDA Guidance for Developing Diabetes Drugs is Affecting Trial Design

07-Dec-2011
News Image In 2008, the US Food and Drug Administration (FDA) issued guidance which means that all antidiabetic drugs to be licensed in the future require thorough assessment of cardiovascular safety...
[Full article]

IDF World Diabetes Congress 2011

06-Dec-2011
News Image Professor Holman gave two invited talks, entitled "Legacy Effect of Improved Glycaemic Control in Type 2 Diabetes" and "Estimating Individual CVD Risk in Type 2 diabetes", at the International Diabetes Federation World Diabetes Congress 2011 meeting in Dubai on Tuesday 6th December...
[Full article]

American Heart Association Scientific Sessions 2011

13-Nov-2011
News Image Professor Holman gave an invited talk entitled "Acarbose: The comeback kid?" at the American Heart Association Scientific Sessions 2011 in Orlando on Sunday 13th November 2011...
[Full article]

Paediatric Endocrinology and Diabetes 2011

11-Nov-2011
News Image Professor Holman gave an invited talk entitled "Acarbose: The comeback kid?" at the 39th Meeting of the British Society for Paediatric Endocrinology and Diabetes (BSPED) in London on Friday 11th November 2011...
[Full article]

Canadian National Atherosclerosis Forum 2011

14-Oct-2011
News Image Professor Holman gave a plenary talk entitled "Key Messages from Cardiovascular Trials in T2DM" at the 13th Canadian National Atherosclerosis Forum on Friday 14th October 2011...
[Full article]

Young Diabetologists Forum 2011

29-Sep-2011
Professor Holman gave a keynote speech entitled "From Research Fellow to International Researcher" at the YDF Research day at the University of Warwick on Thursday 29th September 2011...
[Full article]

Professor Holman gives invited lecture at the 2011 EASD meeting

14-Sep-2011
News Image On the morning of 14 September, Professor Rury Holman gave an invited plenary talk in the session 'Warning signals from clinical trials: all that glitters is not gold' at the 47th meeting of the European Association for the Study of Diabetes (EASD), held in Lisbon, Portugal...
[Full article]

DTU benefits from share of £95m in research funding

13-Sep-2011
Research at the Diabetes Trials Unit is set to benefit from renewed funding of the Oxford Biomedical Research Centre (OxBRC) by the National Institute for Health Research (NIHR)...
[Full article]

ACE Regional Investigator Meetings July 2011

26-Aug-2011
News Image This year's Acarbose Cardiovascular Evaluation (ACE) Regional Investigator Meetings were held between 14th and 21st July in six Chinese cities: Beijing, Chengdu, Hangzhou, Guangzhou, Qingdao and Wuhan...
[Full article]

New offices opened in Beijing

03-Aug-2011
News Image On Friday 15th July 2011 Oxford University (Beijing) Science & Technology Company Ltd...
[Full article]

Insulin treatment satisfaction in the 4-T trial

29-Jul-2011
News Image In Diabetes, Obesity and Metabolism, we investigate how insulin treatment satisfaction varies between biphasic, prandial or basal insulin treatment groups in the Treat-To-Target in Type 2 diabetes (4-T) trial...
[Full article]

EXSCEL launches outside the US

01-Jul-2011
News Image The EXenatide Study of Cardiovascular Event Lowering (EXSCEL) trial was successfully launched outside of the US in May this year, with four Investigator Meetings conducted in May and June in order to initiate sites...
[Full article]

Prof. Holman's international contributions recognised by prestigious American Diabetes Association award

27-Jun-2011
News Image Professor Rury Holman has been awarded the American Diabetes Association's prestigious 2011 Harold Rifkin Award for Distinguished International Service in the Cause of Diabetes...
[Full article]

DREAM trial washout results

15-Jun-2011
News Image In Diabetes Care, we describe how withdrawing rosiglitazone and ramipril medication affects diabetes incidence after the closeout of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial...
[Full article]

A qualitative study of how treatment recommendations are followed in clinical trials

24-May-2011
News Image In the past, qualitative trial research has mainly focused on whether patients and staff understand how trials work, or tried to understand their motivations for taking part...
[Full article]

Rosiglitazone out-performs Metformin and Glyburide in terms of renal function as an early-stage type 2 diabetes treatment

19-Apr-2011
News Image ADOPT (A Diabetes Outcomes Prevention Trial) showed that initial treatment with just rosiglitazone provided more durable glycemic control than metformin or glyburide in patients with recently diagnosed type 2 diabetes...
[Full article]

TECOS initiation meeting in Prague for new members

05-Apr-2011
News Image On the 24 March 2011, the TECOS team arrived in Prague to host the initiation meeting for the new sites in Europe, Israel and South Africa...
[Full article]

Diabetes patients worry about injecting insulin in public more than they do about injecting more frequently

30-Mar-2011
News Image Part of the Treating to Target in Type 2 Diabetes (4-T) trial involved exploring participants' reactions to their intensifying insulin therapy...
[Full article]

More effective glycaemic control seen with rosiglitazone is explained by effects on both β-cell function and insulin sensitivity

22-Mar-2011
News Image The ADOPT study (A Diabetes Outcomes Prevention Trial) showed that treatment with rosiglitazone alone provided somewhat more effective glycaemic control than metformin or glyburide alone, in patients with recently diagnosed type 2 diabetes...
[Full article]

Prof. Rury Holman appointed as an NIHR Senior Investigator

18-Mar-2011
News Image Professor Rury Holman has been appointed as a Senior Investigator by the National Institute for Health Research (NIHR)...
[Full article]

Young Diabetologists Forum Finishing School 'well received'

22-Feb-2011
The third YDF OCDEM Finishing School for Specialist Registrars was held at Eynsham Hall on 10th and 11th February 2011...
[Full article]

Professor Holman gives invited talk at the Royal College of Physicians

16-Feb-2011
News Image Professor Holman gave an invited talk entitled "Management of Type 2 Diabetes in the 21st century" at the Royal College of Physicians Advanced Medicine Conference in London on Wednesday 16th February 2011...
[Full article]

Impact of personalised cardiovascular risk estimates on physical activity

15-Feb-2011
News Image Informing a person of their risk of developing a disease might be suffiicient impetus to change that person's lifestyle...
[Full article]

Professor Rury Holman co-chairs the Young Diabetologists Forum Finishing School

08-Feb-2011
The 2011 YDF-OCDEM Finishing School for Specialist Registrars (an Advanced Diabetes Course, previously known as the YDF-OCDEM State of the Art Course) will be held on 10th and 11th of February at Eynsham Hall near Oxford...
[Full article]

Outcomes Model 1.3 released

21-Jan-2011
News Image Corrected smoking status check and amputation output and added cohort outputs in Standalone version
Smoking status is now calculated once per loop instead of once per patient
Cumulative Event rate output for events has been replaced with Event rate and Long-term history rate
Diabetes related death has been separated into a separate output sheet from other death
A new group column has been added to the Inputs sheet after the ID column...
[Full article]

Variations in the gene ATM affect the performance of metformin

14-Jan-2011
News Image We report in Nature Genetics a genome-wide association study for glycemic response to metformin, the most commonly used pharmacological therapy for type 2 diabetes...
[Full article]

TECOS Update

02-Aug-2010
News Image Since the first subject was enrolled in December 2008, TECOS has witnessed a number of study milestones...
[Full article]

ACE is seeking ancillary study proposals...

22-Jul-2010
News Image ...
[Full article]

NAVIGATOR trial results published

15-Mar-2010
News Image ...
[Full article]

NAVIGATOR valsartan results presented at ACC.10 in Atlanta

14-Mar-2010
News Image Effect of Valsartan on the Incidence of Diabetes and Cardiovascular Events
The NAVIGATOR Study Group
N Engl J Med 2010 on-line (10...
[Full article]

NAVIGATOR nateglinide results presented at ACC.10 in Atlanta

14-Mar-2010
News Image Effect of Nateglinide on the Incidence of Diabetes and Cardiovascular Events
The NAVIGATOR Study Group
N Engl J Med 2010 on-line (10...
[Full article]

NAVIGATOR results slide set

14-Mar-2010
News Image Download a slide deck showing the primary NAVIGATOR results of the effects of nateglinide and valsartan on the incidence of diabetes and cardiovascular events by clicking on the link below...
[Full article]

NAVIGATOR Baseline paper published

02-Mar-2010
News Image Baseline Characteristics of the Nateglinide and Valsartan Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial Population: Comparison with Other Diabetes Prevention Trials
Henry Krum, John J...
[Full article]

Personal Chair awarded to Dr Andrew Farmer

02-Feb-2010
News Image Congratulations to Andrew who has been awarded the title of Professor of General Practice with immediate effect by the University's Recognition of Distinction Committee...
[Full article]

4-T final results published

22-Oct-2009
News Image The final 4-T results were presented during the "Latest clinical trials" symposium at the IDF World Diabetes Congress in Montreal, Canada on Thursday 22nd October 2009...
[Full article]

Final results of the 4-T trial

17-Oct-2009
News Image The final three-year results of the 4-T trial will be presented at 11 am EST on Thursday 22nd October 2009 during the IDF World Diabetes Congress late breaking clinical trial session...
[Full article]

First National ACE Investigator Meeting

11-Oct-2009
News Image ...
[Full article]

TECOS is seeking ancillary study proposals...

09-Oct-2009
News Image ...
[Full article]

Rosiglitazone Decreases C-Reactive Protein

09-Oct-2009
News Image Rosiglitazone Decreases C-Reactive Protein to a Greater Extent Relative to Glyburide and Metformin over Four-Years in Spite of Greater Weight Gain: Observations from ADOPT (A Diabetes Outcome Progression Trial)...
[Full article]

Intensive glucose control and macrovascular outcomes in type 2 diabetes

10-Aug-2009
News Image In order to provide more precise estimates of the effects of glucose-lowering on major cardiovascular events, the Action to Control Cardiovascular Risk in Diabetes (ACCORD), Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE), UKPDS and Veterans Affairs Diabetes Trial (VADT) investigators have established a collaboration to facilitate a formal meta-analysis of the results from each trial and to explore any differences among trials...
[Full article]

4-T database lock

07-Aug-2009
News Image The three-year 4-T Trial last patient visit was completed in July 2009 and the database has been locked...
[Full article]

Optimal insulin regimens in type 2 diabetes mellitus

01-Aug-2009
News Image Greater HbA1c reduction may be obtained in type 2 diabetes when insulin is initiated using biphasic or prandial insulin rather than a basal regimen, but with an unquantified risk of hypoglycaemia...
[Full article]

TECOS launched in Europe

29-Jul-2009
News Image TECOS (Trial Evaluating Cardiovascular Outcomes with Sitagliptin) launched in Europe in June and has recruited 30 participants to date from Hungary, Lithuania & Spain...
[Full article]

HTA report on self-monitoring of blood glucose

25-Jun-2009
News Image We have found no convincing evidence to recommend routine use of SMBG by reasonably well-controlled, non-insulin-treated patients with type 2 diabetes...
[Full article]

Outcomes Model 1.2.1 released

03-Jun-2009
News Image Corrections
Corrected an issue on page 17 of the manual (Example #1) where the example incorrectly stated that the age entered should be 60...
[Full article]

HbA1c for the diagnosis of diabetes?

01-Jun-2009
News Image An International Expert Committee with members appointed by the American Diabetes Association, the European Association for the Study of Diabetes, and the International Diabetes Federation was convened in 2008 to consider the current and future means of diagnosing diabetes in nonpregnant individuals...
[Full article]

2009 Diabetes State of the Art Course presented by OCDEM and YDF

20-May-2009
12th and 13th November 2009

The Young Diabetologists Forum (YDF) and the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) have developed an educational programme for year 4 and year 5 SpRs...
[Full article]

Risk Engine 2.01 released

14-Apr-2009
News Image Fixes a problem in the Macintosh version where male subjects are described as female in the printout, the results printed were, however, correct...
[Full article]

New cardiovascular outcome trial with once-weekly exenatide

28-Mar-2009
A global study, sponsored by Amylin and Lilly, is being planned in conjunction with the Diabetes Trials Unit and the Duke Clinical Research Institute...
[Full article]

First ACE patient enrolled 17th February 2009

19-Feb-2009
News Image ...
[Full article]

Impact of using a non-diabetes-specific risk calculator on eligibility for statin therapy in type 2 diabetes

10-Feb-2009
News Image Price HC, Coleman RL, Stevens RJ, Holman RR
Diabetologia 2009; 52: 394-97

Aims/hypothesis
The aim of this study was to investigate the impact of using a non-diabetes-specific cardiovascular disease (CVD) risk calculator to determine eligibility for statin therapy according to current UK National Institute for Health and Clinical Excellence (NICE) guidelines for those patients with type 2 diabetes who are at an increased risk of CVD (10 year risk ≥20%)...
[Full article]

Commentary on POPADAD study

21-Jan-2009
News Image Primary prevention of cardiovascular events in diabetes: is there a role for aspirin?

Price HC, Holman RR...
[Full article]

Potential impact of omega-3 treatment on cardiovascular disease in type 2 diabetes

13-Jan-2009
News Image Hartweg J, Farmer AJ, Holman RR, Neil A...
[Full article]

AFORRD primary results published

09-Jan-2009
News Image Atorvastatin in Factorial with Omega-3 EE90 Risk Reduction in Diabetes (AFORRD): a randomised controlled trial
R...
[Full article]

Updated version of ADA/EASD consensus algorithm for management of hyperglycaemia

09-Jan-2009
News Image ...
[Full article]

Prevalence of Glucokinase (GCK) Mutations in Individuals Screened for Fasting Hyperglycaemia

09-Jan-2009
News Image ...
[Full article]

TECOS study launched

01-Dec-2008
News Image The Trial to Evaluate Cardiovascular Outcomes after Treatment with Sitagliptin (TECOS) clinical trial launched...
[Full article]

Prevalence of GCK mutations in fasting hyperglycaemia

14-Nov-2008
News Image ...
[Full article]

AFORRD results published online

13-Nov-2008
News Image ...
[Full article]

UKCRC Registered Clinical Trials Units website launched

29-Oct-2008
News Image A new comprehensive online resource listing national expertise in the design and conduct of clinical trials is launched today...
[Full article]

Ethics approval received for the Acarbose Cardiovascular Evaluation (ACE) trial

28-Oct-2008
News Image The ACE trial has received ethics approval from the Oxford Tropical Research Ethics Committee (OXTREC)...
[Full article]

NAVIGATOR Design Paper published

01-Oct-2008
News Image Prevention of diabetes and cardiovascular disease in patients with impaired glucose tolerance: Rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial Rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial

Robert M...
[Full article]

UKPDS shows glucose control and metformin legacy effects

10-Sep-2008
News Image The UKPDS 10-year post-trial monitoring results were presented at the 44th EASD meeting in Rome on Wednesday 10th September 2008...
[Full article]

30-year UKPDS results

07-Sep-2008
News Image The results of the UKPDS post-trial monitoring follow-up are being be presented at the 2008 EASD...
[Full article]

Selecting components for composite endpoints

26-Aug-2008
News Image Determining the most appropriate components for a composite clinical trial outcome

M...
[Full article]

Diabetic Medicine supplement with eleven UKPDS review articles

01-Aug-2008
News Image The August 2008 issue of Diabetic Medicine includes a UKPDS Supplement, edited by Rury Holman and Peter Watkins...
[Full article]

DTU to run sitagliptin outcome trial with DCRI

08-Jun-2008
Merck has signed a letter of intent with Oxford Diabetes Trial Unit and Duke Clinical Research Institute to design and conduct a clinical cardiovascular outcomes study with sitagliptin (JANUVIA)...
[Full article]

Acarbose Cardiovascular Evaluation (ACE) trial launched

11-Apr-2008
News Image The Acarbose Cardiovascular Evaluation (ACE) trial was launched on Friday 11th April 2008 at the 10th South China International Congress of Cardiology in Guangzhou, China...
[Full article]

Banting Memorial Lecture Awarded to Rury Holman

05-Mar-2008
News Image The Diabetes UK (DUK) Banting Memorial Lecture is the highest award bestowed by Diabetes UK...
[Full article]

OCDEM and YDF present ... Diabetes State of the Art Course

08-Feb-2008
30th and 31st October 2008

The Young Diabetologists Forum (YDF) has joined forces with the Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM) to develop an educational programme for Year 4 and 5 SpRs...
[Full article]

ClinicaL Decisions. Management of Type 2 Diabetes

17-Jan-2008
News Image Type 2 Diabetes
This interactive Journal feature presents the case of a 55-year-old woman with type 2 diabetes, obesity, and hypertension, together with three possible treatment options and expert opinion on each...
[Full article]

DTU Laboratory awarded Clinical Pathology Assocation (CPA) accreditation

19-Dec-2007
...

HOMA Calculator 2.2.2 released

12-Dec-2007
News Image Entry of a comma (,) instead of a full stop or period (...
[Full article]

Diabetes Trials Unit awarded full UKCRC CTU Registration

28-Nov-2007
News Image ...
[Full article]

Consensus algorithm update for thiazolidinediones

22-Nov-2007
News Image Management of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy : Update regarding the thiazolidinediones
D...
[Full article]

Recommendations for designing tables that report randomized trials

15-Nov-2007
News Image Recommendations for designing tables that report randomized trials
E...
[Full article]

Outstanding Foreign Investigator Award

14-Nov-2007
News Image Professor Rury Holman, Director of the Diabetes Trials Unit at Oxford University, has been awarded the 'Outstanding Foreign Investigator Award' by the Japan Society of Diabetic Complications...
[Full article]

Metabolic syndrome and Type 2 diabetes - UKPDS Paper 78

30-Oct-2007
News Image Impact of the Metabolic Syndrome on Macrovascular and Microvascular Outcomes in Type 2 Diabetes Mellitus...
[Full article]

4-T One Year results published in NEJM

25-Oct-2007
News Image The 4-T One-Year results were presented as a "late breaking trial" at the 43rd EASD meeting in Amsterdam on 21st September 2007...
[Full article]

HOMA Calculator 2.2.1 released

23-Oct-2007
News Image Fixes a minor problem running the HOMA Calculator on Windows where the allowed ranges for Insulin, Specific Insulin and C-Peptide would be reported with SI units rather than the alternatives...
[Full article]

Risk Engine confidence interval methodology published

05-Sep-2007
News Image ...
[Full article]

Stability of Soluble Adhesion Molecules, Selectins, and C-Reactive Protein at Various Temperatures

07-Aug-2007
News Image Stability of soluble adhesion molecules, selectins and C-reactive protein at various temperatures: implications for epidemiological and large-scale clinical studies
Janine Hartweg, Michael Gunter, Rafael Perera, Andrew Farmer, Carole Cull, Casper Schalkwijk, Astrid Kok, Harry Twaalfhoven, Rury Holman and Andrew Neil
Clinical Chemistry 2007;53:1858-60...
[Full article]

Omega-3 PUFA effects on emerging lipid cardiovascular risk markers in type 2 diabetes

01-Aug-2007
News Image Meta-analysis of the effects of omega-3 polyunsaturated fatty acids on lipoproteins, lipolytic action, oxidation, lipid ratios and other emerging lipid cardiovascular risk markers in type 2 diabetes
J...
[Full article]

GAD autoantibodies and epitope reactivities in T2DM (UKPDS 77)

29-Jul-2007
News Image GAD autoantibodies and epitope reactivities persist after diagnosis in latent autoimmune diabetes in adults but do not predict disease progression: UKPDS 77...
[Full article]

Self blood glucose monitoring in type 2 diabetes - the DiGEM study

24-Jul-2007
News Image Impact of self monitoring of blood glucose in the management of patients with non-insulin treated diabetes: open parallel group randomised trial
Andrew Farmer, Alisha Wade, Elizabeth Goyder, Patricia Yudkin, David French, Anthea Craven, Rury Holman, Ann-Louise Kinmonth, Andrew Neil on behalf of the Diabetes Glycaemic Education and Monitoring Trial Group
British Medical Journal 2007;335:132-6...
[Full article]

UKPDS Outcomes Model version 1.2 available

21-Jun-2007
News Image Changes in Version 1...
[Full article]

Sad news - Carole Cull died on the 9th June 2007

09-Jun-2007
...
[Link]

Framingham, SCORE and DECODE CVD risk estimates in type 2 diabetes

01-May-2007
News Image Framingham, SCORE and DECODE do not provide reliable cardiovascular risk estimates in type 2 diabetes
Ruth L...
[Full article]

Omega-3 PUFA effects on haematological and thrombogenic factors in type 2 diabetes

30-Jan-2007
News Image Meta-analysis of the effects of omega-3 poylunsaturated fatty acids on haematological and thrombogenic factors in type 2 diabetes
J...
[Full article]

Association Analysis of the HLA Gene Region in LADA

30-Jan-2007
News Image An Association Analysis of the HLA Gene Region in Latent Autoimmune Diabetes in Adults
M...
[Full article]

AFORRD results presented at IDF WDC2006 Cape Town

07-Dec-2006
News Image The results of the AFORRD trial were presented at the International Diabetes Federation Congress in Cape Town on Thursday 7th December 2006
A copy of the press release is attached...
[Full article]

DREAM drug washout study results

07-Dec-2006
News Image DREAM drug washout study results released at IDF WDC2006 Cape Town...
[Full article]

PON2 polymorphisms and renal dysfunction (UKPDS 76)

17-Nov-2006
News Image Paraoxonase2 (PON2) Polymorphisms and Development of Renal Dysfunction in Type 2 Diabetes: UKPDS 76
Calle R, McCarthy MI, Banerjee P, Zeggini E, Cull CA, Thorne KI, Wiltshire S, Terra S, Meyer D, Richmond J, Mancuso J, Milos P, Fryburg D, Holman RR
Diabetologia 2006;49:2892-2899...
[Full article]

Characteristics of Type 2 diabetic patients in North America and Europe (ADOPT)

17-Nov-2006
News Image A Diabetes Outcome Progression Trial (ADOPT): baseline characteristics of Type 2 diabetic patients in North America and Europe
Viberti G, Lachin J, Holman R, Zinman B, Haffner S, Kravitz B, Heise MA, Jones NP, O'Neill MC, Freed MI, Kahn SE, Herman WH for the ADOPT Study Group
Diabetic Medicine 2006;23:1289-1294...
[Full article]

Is there a need for a clinical screening tool for autoimmune diabetes in adults?

30-Oct-2006
...
[Link]

Hypoglycaemia in type 2 diabetes (UKPDS 73)

26-Oct-2006
News Image Hypoglycemia in Type 2 diabetic patients randomized to and maintained on monotherapy with diet, sulfonylurea, metformin, or insulin for 6 years from diagnosis: UKPDS 73
Wright AD, Cull CA, Macleod KM, Holman RR for the UKPDS Group
Journal of Diabetes and its Complications 2006;20:402-408...
[Full article]

Download DREAM trial results slides

15-Sep-2006
News Image ...
[Full article]

DREAM trial results

13-Sep-2006
News Image ...
[Full article]

Obesity and CRP in type 2 diabetes (ADOPT)

01-Aug-2006
News Image Obesity is a major determinant of the association of C-reactive protein levels and the metabolic syndrome in type 2 diabetes
Steven E...
[Full article]

Impact of glycemic control on macrovascular disease

05-Jul-2006
News Image Glycemic control and macrovascular disease in types 1 and 2 diabetes mellitus: Meta-analysis of randomized trials
Christoph Stettler, Sabin Allemann, Peter Jüni, Carole A...
[Full article]

ADA/EASD consensus algorithm for managing hyperglycaemia

29-Jun-2006
News Image Management of Hyperglycemia in Type 2 Diabetes: A Consensus Algorithm for the Initiation and Adjustment of Therapy
David M Nathan, John B Buse, Mayer B Davidson, Robert J Heine, Rury R Holman, Robert Sherwin, Bernard Zinman

Published simultaneously in:

Diabetes Care (2006); 29: 1963-1972

and

Diabetologia (2006); 49: 1711-1721...
[Full article]

Impact of Visual Acuity on Quality of Life

28-Jun-2006
News Image Assessing the Impact of Visual Acuity on Quality of Life in Individuals With Type 2 Diabetes Using the Short Form-36
Philip M Clarke, Judit Simon, Carole A Cull, Rury R Holman
Diabetes Care 2006; 29: 1506-1511

OBJECTIVE- We sought to ascertain quality-of-life measures and utility values associated with visual acuity in type 2 diabetes...
[Full article]

Combined effects of glycaemia and blood pressure in type 2 diabetes (UKPDS 75)

01-Jun-2006
News Image Additive effects of glycaemia and blood pressure exposure on risk of complications in type 2 diabetes: a prospective observational study (UKPDS 75)
I...
[Full article]

VNTR and LADA susceptibility

31-May-2006
News Image The Variable Number of Tandem Repeats Upstream of the Insulin Gene Is a Susceptibility Locus for Latent Autoimmune Diabetes in Adults
Minal Desai, Eleftheria Zeggini, Virginia A...
[Full article]

Risk factors for renal dysfunction (UKPDS 74)

30-May-2006
News Image Risk Factors for Renal Dysfunction in Type 2 Diabetes : UK Prospective Diabetes Study 74
Ravi Retnakaran, Carole A...
[Full article]

Joint Servier/OCDEM Meeting for Specialist Registrars

15-May-2006
News Image Beyond The Boundary
Cutting Edge Issues for Emerging Diabetologists...
[Full article]

Thames Valley Diabetes Research Network

15-May-2006
News Image Oxford University researchers and the Oxford Radcliffe Hospitals Trust will lead one of eight new Local Research Networks for diabetes across the UK, working with hospitals and patients throughout the Thames Valley area to develop prevention methods and treatments for diabetes...
[Full article]

Long-term efficacy of sulfonylureas

04-May-2006
News Image Long-term efficacy of sulfonylureas: a United Kingdom Prospective Diabetes Study perspective
Rury R...
[Full article]

Comment on PROactive study results

07-Jan-2006
Lancet 2006; 367:25-26

RR Holman, R Retnakaran, A Farmer and R Stevens

The PROactive study has provided an exploratory estimate of the relative risk reduction attributable to pioglitazone for a composite endpoint of all-cause mortality, non-fatal myocardial infarction, and stroke...
[Full article]

UKPDS Outcomes Model manual available online

01-Oct-2005
News Image The UKPDS Outcomes Model manual is now available online providing a more detaile view of its functionality and likely uses...
[Full article]

UKPDS Outcomes Model 1.1 released

09-Sep-2005
News Image ...
[Full article]

Reporting of diabetes on death certificates

15-Jul-2005
News Image Reporting of diabetes on death certificates using data from the UK Prospective Diabetes Study
M...
[Full article]

Non-HDL Cholesterol Is Less Informative

25-Jun-2005
News Image Non-HDL Cholesterol Is Less Informative Than the Total-to-HDL Cholesterol Ratio in Predicting Cardiovascular Risk in Type 2 Diabetes
Rury R...
[Full article]

UKPDS paper 72 published in Diabetologia

24-May-2005
News Image Cost-utility analyses of intensive blood glucose and tight blood pressure control in type 2 diabetes (UKPDS 72)
P...
[Full article]

Glycaemic control after addition of sulphonylurea to metformin

05-May-2005
News Image Glycemic Control Continues to Deteriorate After Sulfonylureas Are Added to Metformin Among Patients With Type 2 Diabetes
Michael N Cook, Cynthia J Girman, Peter P Stein, Charles M Alexander & Rury R Holman
Diabetes Care (2005); 28: 995-1000

OBJECTIVE— To describe the course and predictors of glycemic control among patients with type 2 diabetes after sulfonylureas (SUs) are added to metformin (MF)...
[Full article]

UKPDS paper 70 published in Diabetologia

20-Apr-2005
News Image Islet autoantibodies in clinically diagnosed type 2 diabetes: prevalence and relationship with metabolic control
T...
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UKPDS paper 71 published in Diabetologia

20-Apr-2005
News Image IA-2 antibody prevalence and risk assessment of early insulin requirement in subjects presenting with type 2 diabetes
G...
[Full article]

UKPDS paper 67 published in Diabetic Medicine

22-Feb-2005
News Image Insulin sensitivity at diagnosis of Type 2 diabetes is not associated with subsequent cardiovascular disease (UKPDS 67)...
[Full article]

Framingham risk equations can underestimate CHD risk in diabetes

20-Jan-2005
News Image Framingham risk equations underestimate coronary heart disease risk in diabetes
R...
[Full article]

UKPDS Outcomes Model software 1.0 released

01-Dec-2004
News Image ...
[Full article]

Paper on aspirin use in Type 2 diabetes published in Diabetic Medicine

01-Dec-2004
News Image Changing aspirin use in patients with Type 2 diabetes in the UKPDS
Cull CA, Neil HA, Holman RR
Diabetic Medicine 2004; 21:1368-71

AIMS: To examine the proportion of UK Prospective Diabetes Study (UKPDS) patients with Type 2 diabetes taking aspirin regularly for the primary and secondary prevention of cardiovascular disease (CVD) before and after publication of the 1997 American Diabetes Association (ADA) Clinical Practice Recommendations and the 1998 Joint British Recommendations on the Prevention of Coronary Disease in Clinical Practice...
[Full article]

GADA prevalence in type 2 diabetes (ADOPT)

01-Dec-2004
News Image Phenotypic characteristics of GAD antibody-positive recently diagnosed patients with type 2 diabetes in North America and Europe
Zinman B, Kahn SE, Haffner SM, O'Neill MC, Heise MA, Freed MI; ADOPT Study Group
Diabetes 2004;53:3193-3200...
[Full article]

UKPDS paper 69 published in Archives of Ophthalmology

01-Nov-2004
News Image Risks of progression of retinopathy and vision loss related to tight blood pressure control in type 2 diabetes mellitus: UKPDS 69...
[Full article]

AFORRD Study commences recruitment

01-Nov-2004
News Image The Atorvastatin in Factorial with Omega-3 fatty acids Risk Reduction in Diabetes (AFORRD) study began recruiting participants on Monday 1st November 2004...
[Full article]

4-T Study commences recruitment

01-Nov-2004
News Image The Treating To Target in Type 2 Diabetes (4-T) study began recruiting participants on Monday 1st November 2004...
[Full article]

UKPDS paper 68 published in Diabetologia

01-Oct-2004
News Image A model to estimate the lifetime health outcomes of patients with type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS 68)
P...
[Full article]

DREAM protocol paper published in Diabetologia

01-Sep-2004
News Image Rationale, design and recruitment characteristics of a large, simple international trial of diabetes prevention: the DREAM trial
Gerstein HC, Yusuf S, Holman RR, Bosch J, Pogue J; The DREAM Trial Investigators
Diabetologia 2004;47:1519-1527

AIMS/HYPOTHESIS: Diabetes is a rapidly rising independent risk factor for atherosclerosis and serious illness...
[Full article]

HOMA Calculator 2.2 released

30-Jun-2004
News Image The HOMA Calculator has been updated to provide HOMA2 IR values automatically, in addition to HOMA2 %S and HOMA2 %B...
[Full article]

HOMA Calculator released

01-Jun-2004
News Image The HOMA Calculator provides quick and easy access to the HOMA model for researchers who wish to use model-derived estimates of beta cell function ( %B), insulin sensitivity (%S) or insulin resistance (HOMA IR), rather than linear approximations...
[Full article]

UKPDS Risk Engine 2.0 released

26-Feb-2004
News Image Version 2...
[Full article]

OTTT paper published in Diabetes Care

01-Jan-2004
News Image A Standardized Triglyceride and Carbohydrate Challenge...
[Full article]

The AFORRD study

01-Jan-2004
News Image The Atorvastatin in Factorial with Omega-3 fatty acids Risk Reduction in Diabetes (AFORRD) study is assessing the degree to which a statin and/or omega-3 fatty acids are likely to reduce coronary heart disease (CHD) risk in people with Type 2 diabetes...
[Full article]

UKPDS paper 66 published in Diabetes Care

01-Jan-2004
News Image Risk Factors for Myocardial Infarction Case Fatality and Stroke Case Fatality in Type 2 Diabetes...
[Full article]

New UKPDS results reported at the IDF

23-Sep-2003
News Image ...
[Full article]

Risk Engine 1.2 released

20-Aug-2003
News Image Fixes a minor issue with the help button on machines using Internet Explorer as the default browser on the Windows platform...
[Full article]

Full programme for third Mount Hood meeting announced

18-Jul-2003
...
[Link]

The Mount Hood III modelling meeting will be hosted by the DTU in Oxford in August

10-Jun-2003
...

UKPDS paper 65 published in Diabetic Medicine

04-Jun-2003
News Image The impact of diabetes-related complications on healthcare costs: results from the United Kingdom Prospective Diabetes Study (UKPDS Study No...
[Full article]

UKPDS report on pregnancy outcomes

04-Jun-2003
News Image Poor pregnancy outcome for women with Type 2 diabetes...
[Full article]

Risk Engine 1.1 released

09-May-2003
News Image Accepts lipid levels in mg/dl as well as mmol/l...
[Full article]

Autoantibodies to islet cell antigen SOX-13 paper published in Diabetic Medicine

11-Mar-2003
News Image Autoantibodies to the islet cell antigen SOX-13 are associated with duration but not type of diabetes...
[Full article]

Move to new Institute

24-Feb-2003
News Image On Monday 24th February we moved into our new, purpose built, Oxford Centre for Diabetes, Endocrinology and Metabolism...
[Full article]

UKPDS paper 64 published in Kidney International

15-Jan-2003
News Image UKPDS 64 Development and Progression of Nephropathy in Type 2 Diabetes: Observation and Modelling from the United Kingdom Prospective Diabetes Study
Adler AI, Stevens RJ, Manley SE, Bilous RW, Cull CA, Holman RR
Kidney International (2003); 63: 225-232

BACKGROUND: The progression of nephropathy from diagnosis of type 2 diabetes has not been well described from a single population...
[Full article]

ISAT Trial results published

26-Oct-2002
News Image The results of the ISAT trial have been published in The Lancet...
[Full article]

EuroDREAM project office

17-Sep-2002
News Image The Diabetes Trials Unit has set up a EuroDREAM project office to help manage those european clinical centres that are participating in the DREAM study...
[Full article]

UKPDS paper 60 published in Stroke

09-Jul-2002
News Image UKPDS 60 Risk of stroke in type 2 diabetes estimated by the UKPDS risk engine
Kothari V, Stevens RJ, Adler AI, Stratton IM, Manley SE, Neil HAW, Holman RR
Stroke (2002); 33: 1776-1781...
[Full article]

DTU abstracts at ADA 2002

07-Jun-2002
News Image Retinopathy in Type 2 Diabetes - When Does the Clock Start Ticking? Rury R Holman, Susan E Manley, Andrew E Neil, David R Matthews and Irene M Stratton...
[Full article]

Appointment of the first Robert Turner Professor of Diabetes

24-May-2002
News Image Professor Mark McCarthy, currently Professor of Genomic Medicine at Imperial College, London and Honorary Consultant Physician at St Mary's Hospital, has been elected to the newly created Robert Turner Professorship of Diabetic Medicine...
[Full article]

UKPDS Risk Engine FAQ available

23-May-2002
News Image A list of frequently asked questions (FAQ) and answers is now available...
[Full article]

Homocysteine as a risk factor for cardiovascular disease publication

08-May-2002
News Image Underestimation of the importance of homocysteine as a risk factor for cardiovascular disease in epidemiological studies...
[Full article]

LDS Close out

26-Mar-2002
News Image Following the withdrawal of cerivastatin by Bayer in August 2001, the Lipids in Diabetes Study (LDS) was put on hold and the 4191 randomised subjects asked to stop all study medication temporarily...
[Full article]

UKPDS Risk Engine v1.0 released

26-Mar-2002
News Image Version 1...
[Full article]

FHS results presented in Jerusalem

19-Sep-2000
News Image The results of the FHS trial where presented at the EASD meeting in Jerusalem...
[Full article]

FHS sulphonylurea paper published

01-Dec-1997
News Image Randomised controlled trial of sulphonylurea therapy for subjects with increased fasting glucose levels
FHS group, Karunakaran S, Hammersley MS, Morris RJ, Turner RC, Holman RR
Metabolism 1997;46:56-60...
[Full article]

FHS healthy-living paper published

01-Dec-1997
News Image Randomised controlled trial of enforced healthy-living advice in subjects with increased but not diabetic fasting glucose
Fasting hyperglycaemia Study Group, Dyson PA, Hammersley MS, Morris RJ, Holman RR, Turner RC
Metabolism 1997;46:50-55...
[Full article]

FHS overview paper published

01-Dec-1997
News Image Subject Identification and Recruitment for a non-insulin-dependent diabetes prevention trial
Fasting Hyperglycaemia Study group, Hammersley MS, Meyer LC, Morris RJ, Manley SE
Metabolism 1997;46:44-49...
[Full article]