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Publications (17 of 405)


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2016

Pancreatic Safety of Sitagliptin in the TECOS Study.
Buse JB, Bethel MA, Green JB, Stevens SR, Lokhnygina Y, Aschner P, Grado CR, Tankova T, Wainstein J, Josse R, Lachin JM, Engel SS, Patel K, Peterson ED, Holman RR; TECOS Study Group.
Diabetes Care 2016;40:164-170. Published:Feb-2017. Epub:14-Sep-2016. PMID:27630212. doi:10.2337/dc15-2780

Evaluation of the Efficacy, Safety, and Glycaemic Effects of Evolocumab (AMG 145) in Hypercholesterolaemic Patients Stratified by Glycaemic Status and Metabolic Syndrome.
Blom DJ, Koren MJ, Roth E, Monsalvo ML, Djedjos CS, Nelson P, Elliott M, Wasserman SM, Ballantyne CM, Holman RR.
Diabetes, Obesity and Metabolism 2016;19:98-107. Published:Jan-2017. Epub:13-Sep-2016. PMID:27619750. doi:10.1111/dom.12788

Sitagliptin and Risk of Fractures in Type 2 Diabetes: Results from the TECOS Trial
Josse RG, Majumdar SR, Zheng Y, Adler A, Bethel MA, Buse JB, Green JB, Kaufman KD, Rodbard HW, Tankova T, Westerhout CM, Peterson ED, Holman RR, Armstrong PW; TECOS Study Group
Diabetes Obes Metab 2016;19:78-86.. Published:Jan-2017. Epub:08-Sep-2016. PMID:27607571. doi:10.1111/dom.12786

Effect of Sitagliptin on Kidney Function and Respective Cardiovascular Outcomes in Type 2 Diabetes: Outcomes From TECOS
Jan H. Cornel, George L. Bakris, Susanna R. Stevens, Michael Alvarsson, Willem A. Bax, Lee-Ming Chuang, Samuel S. Engel, Renato D. Lopes, Darren K. McGuire, Axel Riefflin, Helena Wachslicht Rodbard, Isaac Sinay, Tsvetalina Tankova, Julio Wainstein, Eric D. Peterson, and Rury R. Holman, on behalf of the TECOS Study Group
Diabetes Care 2016;39:2304-2310. Published:Dec-2016. Epub:14-Oct-2016. PMID:27742728. doi:10.2337/dc16-1415

Neurokinin B Receptor Antagonism in Women with Polycystic Ovary Syndrome: A Randomized, Placebo- Controlled Trial
Jyothis T George, Rahul Kakkar, Jayne Marshall, Martin L Scott, Richard D Finkelman, Tony W Ho, Johannes Veldhuis, Karolina Skorupskaite, Richard A Anderson, Stuart McIntosh, Lorraine Webber
J Clin Endocrinol Metab 2016;101:4313-4321. Published:Nov-2016. Epub:26-Jul-2016. doi:10.1210/jc.2016-1202

Effect of metformin therapy on circulating amino acids in a randomized trial: the CAMERA study: Metabolism
D. Preiss, N. Rankin, P. Welsh, R. R. Holman, A. J. Kangas, P. Soininen, P. Würtz, M. Ala-Korpela and N. Sattar
Diabetic Medicine 2016;33:1569-1574. Published:Nov-2016. Epub:16-Feb-2016. PMID:26887663. doi:10.1111/dme.13097

The effect of a brief action planning intervention on adherence to double-blind study medication, compared to a standard trial protocol, in the Atorvastatin in Factorial with Omega EE90 Risk Reduction in Diabetes (AFORRD) clinical trial: a cluster randomised sub-study
Andrew J. Farmer, Jason Oke, Wendy Hardeman, Lynne Tucker, Stephen Sutton, Ann-Louise Kinmonth, Simon Griffin, Rury R. Holman
Diabetes Research and Clinical Practice 2016;120:56-64. Published:Oct-2016. Epub:30-Jul-2016. PMID:27522034. doi:10.1016/j.diabres.2016.07.004

Variation in the glucose transporter gene SLC2A2 is associated with glycemic response to metformin
Kaixin Zhou, Sook Wah Yee, Eric L Seiser, Nienke van Leeuwen, Roger Tavendale, Amanda J Bennett, Christopher J Groves, Ruth L Coleman, Amber A van der Heijden, Joline W Beulens, Catherine E de Keyser, Linda Zaharenko, Daniel M Rotroff, Mattijs Out, Kathleen A Jablonski, Ling Chen, Martin Javorsky?, Jozef Židzik, Albert M Levin, L Keoki Williams, Tanja Dujic, Sabina Semiz, Michiaki Kubo, Huan-Chieh Chien, Shiro Maeda, John S Witte, Longyang Wu, Ivan Tkác?19, Adriaan Kooy, Ron H N van Schaik, Coen D A Stehouwer, Lisa Logie, MetGen Investigators, DPP Investigators, ACCORD Investigators, Calum Sutherland, Janis Klovins, Valdis Pirags, Albert Hofman, Bruno H Stricker, Alison A Motsinger-Reif, Michael J Wagner, Federico Innocenti, Leen M ’t Hart, Rury R Holman, Mark I McCarthy, Monique M Hedderson, Colin N A Palmer, Jose C Florez, Kathleen M Giacomini & Ewan R Pearson
Nature Genetics 2016;48:1055-9. Published:Sep-2016. Epub:08-Aug-2016. PMID:27500523. doi:10.1038/ng.3632

Toward Fairness in Data Sharing
The International Consortium of Investigators for Fairness in Trial Data Sharing
N Engl J Med 2016;375:405-407. Published:04-Aug-2016. doi:10.1056/NEJMp1605654

Preface – Diabetes prevention and management
Rury R. Holman
Best Pract Res Clin Endocrinol Metab. 2016;30:329. Published:Jun-2016. Epub:16-Jul-2016. doi:10.1016/j.beem.2016.07.001

This house believes that sulphonylureas should not be used routinely as second-line treatments for patients with type 2 diabetes
Gwilt M, Ryder REJ, Holman RR
British Journal of Diabetes 2016;16:88-92. Published:Jun-2016. doi:10.15277/bjd.2016.082

Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus
Darren K. McGuire,MD, MHSc; Frans Van deWerf, MD, PhD; PaulW. Armstrong, MD; Eberhard Standl, MD, PhD; Joerg Koglin, MD; Jennifer B. Green, MD; M. Angelyn Bethel, MD; Jan H. Cornel, MD; Renato D. Lopes, MD, MHS, PhD; Sigrun Halvorsen, MD; Giuseppe Ambrosio, MD; John B. Buse, MD; Robert G. Josse, MBBS; John M. Lachin, ScD; Michael J. Pencina, PhD; Jyotsna Garg, MS; Yuliya Lokhnygina, PhD; Rury R. Holman, MBChB; Eric D. Peterson, MD, MPH; for the Trial Evaluating Cardiovascular Outcomes With Sitagliptin (TECOS) Study Group
JAMA Cardiology 2016;1:126-135. Published:May-2016. Epub:13-Apr-2016. doi:10.1001/jamacardio.2016.0103

Rationale for and design of the Acarbose Cardiovascular Evaluation (ACE) trial [Mandarin republication]
Rury R Holman, Mary A Bethel, Juliana CN Chan, Jean-Louis Chiasson, Zoë Doran, Junbo Ge, Hertzel Gerstein, Yong Huo, John J McMurray, Lars Ryden, Winitha Liyanage, Stefan Schröder, Michal Tendera, Michael J Theodorakis, Jaakko Tuomilehto, Wenying Yang, Dayi Hu, Changyu Pan for the ACE Study Group
Int J Endocrinol Metab 2016;36:1-4. Published:May-2016. doi:10.3760/cma.j.issn.1673-4157.201.00.00

Rationale and Design of the EXenatide Study of Cardiovascular Event Lowering (EXSCEL) Trial
Rury R. Holman, M. Angelyn Bethel, Jyothis George, Harald Sourij, Zoë Doran, Joanne Keenan, Nardev S. Khurmi, Robert J. Mentz, Abderrahim Oulhaj, John B. Buse, Juliana C. Chan, Nayyar Iqbal, Sudeep Kundu, Aldo P. Maggioni, Steven P. Marso, Peter Öhman, Michael J. Pencina, Neil Poulter, Lisa E. Porter, Ambady Ramachandran, Bernard Zinman, Adrian F.Hernande
American Heart Journal 2016;174:103-110. Published:Apr-2016. Epub:21-Dec-2015. doi:10.1016/j.ahj.2015.12.009

Adherence to Oral Glucose-Lowering Therapies and Associations With 1-year HbA1c: A Retrospective Cohort Analysis in a Large Primary Care Database
Andrew J. Farmer, Lauren R Rodgers, Mike Lonergan, Beverley Shields, Michael Weedon, Louise Donnelly, Rury R. Holman, Ewan R. Pearson, Andrew T Hattersley for the MASTERMIND consortium
Diabetes Care 2016;39:258-263. Published:Feb-2016. Epub:17-Dec-2015. PMID:26681714. doi:10.2337/dc15-1194

Randomized controlled trial comparing impact on platelet reactivity of twice-daily with once-daily aspirin in people with Type 2 diabetes
M.A. Bethel, P Harrison, H Sourij, Y Sun, L Tucker, I Kennedy , S White, L Hill, A Oulhaj, R Coleman, R.R. Holman
Diabetic Medicine 2016;33:224-230. Published:Feb-2016. Epub:14-Jul-2015. PMID:26043186. doi:10.1111/dme.12828

On the potential of acarbose to reduce cardiovascular disease [Mandarin republication]
Standl E, Theodorakis MJ, Erbach M, Schnell O, Tuomilehto J, Pan CY
Int J Endocrinol Metab 2016;36:3-4. Published:Jan-2016. doi:10.3760/cma.j.issn.1673-4157.2016.01.001