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Trial Evaluating Cardiovascular Outcomes With Sitagliptin

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Publications (15 of 15)


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In-press or Epub

Modelling incremental benefits on complications rates when targeting lower HbA1c levels in people with Type 2 diabetes and cardiovascular disease
Mostafa SA, Coleman RL, Agbaje OF, Gray AM, Holman RR, Bethel MA
Diabet Med. 2017. Epub:23-Oct-2017. PMID:29057545. doi:10.1111/dme.13533

Causes of Death in a Contemporary Cohort of Patients With Type 2 Diabetes and Atherosclerotic Cardiovascular Disease: Insights From the TECOS Trial
Abhinav Sharma, Jennifer B. Green, Allison Dunning, Yuliya Lokhnygina, Sana M. Al-Khatib, Renato D. Lopes, John B. Buse, John M. Lachin, Frans Van de Werf, Paul W. Armstrong, Keith D. Kaufman, Eberhard Standl, Juliana C.N. Chan, Larry A. Distiller, Russell Scott, Eric D. Peterson, and Rury R. Holman, on behalf of the TECOS Study Group
Diabetes Care 2017. Epub:06-Oct-2017. doi:10.2337/dc17-1091

2017

Hypertension Control in Adults With Diabetes Mellitus and Recurrent Cardiovascular Events: Global Results From the Trial Evaluating Cardiovascular Outcomes With Sitagliptin
Navar AM, Gallup DS, Lokhnygina Y, Green JB, McGuire DK, Armstrong PW, Buse JB, Engel SS, Lachin JM, Standl E, Van de Werf F, Holman RR, Peterson ED
Hypertension 2017;70:907-914. Published:Nov-2017. Epub:28-Aug-2017. PMID:28847886. doi:10.1161/HYPERTENSIONAHA.117.09482

Safety of Sitagliptin in Patients with Type 2 Diabetes and Chronic Kidney Disease: Outcomes from TECOS
Engel SS, Suryawanshi S, Stevens SR, Josse RG, Cornel JH, Jakuboniene N, Riefflin A, Tankova T, Wainstein J, Peterson ED, Holman RR; TECOS Study Group
Diabetes Obes Metab. 2017;19:1587–1593. Published:Nov-2017. Epub:22-Apr-2017. PMID:28432745. doi:10.1111/dom.12983

Secondary Prevention of Cardiovascular Disease in Patients with Type 2 Diabetes: International 2 Insights from the TECOS Trial
Neha J. Pagidipati, Ann Marie Navar, Karen S. Pieper, Jennifer B. Green, M. Angelyn Bethel, Paul W. Armstrong, Robert G. Josse, Darren K. McGuire, Yuliya Lokhnygina, Jan H. Cornel, Sigrun Halvorsen, Timo E. Strandberg, Tuncay Delibasi, Rury R. Holman, Eric D. Peterson, On behalf of the TECOS Study Group
Circulation 2017;136:1193–1203. Published:26-Sep-2017. Epub:16-Jun-2017. PMID:28626088. doi:10.1161/CIRCULATIONAHA.117.027252

Corrections needed to 2016 ESC and AHA guidelines on heart failure
Lars Rydén, Frans Van de Werf, Paul W Armstrong, Darren K McGuire, Eberhard Standl, Eric D Peterson, Rury R Holman
Lancet Diabetes Endocrinol. 2017;5:325-326. Published:May-2017. Epub:05-Apr-2017. PMID:28395875. doi:10.1016/S2213-8587(17)30102-X

Assessing the Safety of Sitagliptin in Older Participants in the Trial Evaluating Cardiovascular Outcomes With Sitagliptin (TECOS)
M. Angelyn Bethel, Samuel S. Engel, Jennifer B. Green, Zhen Huang, Robert G. Josse, Keith D. Kaufman, Eberhard Standl, Shailaja Suryawanshi, Frans Van de Werf, Darren K. McGuire, Eric D. Peterson, Rury R. Holman, for the TECOS Study Group
Diabetes Care 2017;40:494–501. Published:Apr-2017. Epub:05-Jan-2017. PMID:28057693. doi:10.2337/dc16-1135

2016

Pancreatic Safety of Sitagliptin in the TECOS Study.
Buse JB, Bethel MA, Green JB, Stevens SR, Lokhnygina Y, Aschner P, Grado CR, Tankova T, Wainstein J, Josse R, Lachin JM, Engel SS, Patel K, Peterson ED, Holman RR; TECOS Study Group.
Diabetes Care 2016;40:164-170. Published:Feb-2017. Epub:14-Sep-2016. PMID:27630212. doi:10.2337/dc15-2780

Sitagliptin and Risk of Fractures in Type 2 Diabetes: Results from the TECOS Trial
Josse RG, Majumdar SR, Zheng Y, Adler A, Bethel MA, Buse JB, Green JB, Kaufman KD, Rodbard HW, Tankova T, Westerhout CM, Peterson ED, Holman RR, Armstrong PW; TECOS Study Group
Diabetes Obes Metab 2016;19:78-86.. Published:Jan-2017. Epub:08-Sep-2016. PMID:27607571. doi:10.1111/dom.12786

Effect of Sitagliptin on Kidney Function and Respective Cardiovascular Outcomes in Type 2 Diabetes: Outcomes From TECOS
Jan H. Cornel, George L. Bakris, Susanna R. Stevens, Michael Alvarsson, Willem A. Bax, Lee-Ming Chuang, Samuel S. Engel, Renato D. Lopes, Darren K. McGuire, Axel Riefflin, Helena Wachslicht Rodbard, Isaac Sinay, Tsvetalina Tankova, Julio Wainstein, Eric D. Peterson, and Rury R. Holman, on behalf of the TECOS Study Group
Diabetes Care 2016;39:2304-2310. Published:Dec-2016. Epub:14-Oct-2016. PMID:27742728. doi:10.2337/dc16-1415

Association Between Sitagliptin Use and Heart Failure Hospitalization and Related Outcomes in Type 2 Diabetes Mellitus
Darren K. McGuire,MD, MHSc; Frans Van deWerf, MD, PhD; PaulW. Armstrong, MD; Eberhard Standl, MD, PhD; Joerg Koglin, MD; Jennifer B. Green, MD; M. Angelyn Bethel, MD; Jan H. Cornel, MD; Renato D. Lopes, MD, MHS, PhD; Sigrun Halvorsen, MD; Giuseppe Ambrosio, MD; John B. Buse, MD; Robert G. Josse, MBBS; John M. Lachin, ScD; Michael J. Pencina, PhD; Jyotsna Garg, MS; Yuliya Lokhnygina, PhD; Rury R. Holman, MBChB; Eric D. Peterson, MD, MPH; for the Trial Evaluating Cardiovascular Outcomes With Sitagliptin (TECOS) Study Group
JAMA Cardiology 2016;1:126-135. Published:May-2016. Epub:13-Apr-2016. doi:10.1001/jamacardio.2016.0103

2015

Sitagliptin and Cardiovascular Outcomes in Type 2 Diabetes
Rury R. Holman, Eric D. Peterson
The New England Journal of Medicine 2015;373:2479. Published:17-Dec-2015. PMID:26672857. doi:10.1056/NEJMc1510995

Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes
Jennifer B. Green, M. Angelyn Bethel, Paul W. Armstrong, John B. Buse, Samuel S. Engel, Jyotsna Garg, Robert Josse, Keith D. Kaufman, Joerg Koglin, Scott Korn, John M. Lachin, Darren K. McGuire, Michael J. Pencina, Eberhard Standl, Peter P. Stein, Shailaja Suryawanshi, Frans Van de Werf, Eric D. Peterson, and Rury R. Holman, on behalf of the TECOS Study Group
N Engl J Med 2015;373:232-242. Published:16-Jul-2015. Epub:08-Jun-2015. PMID:26052984. doi:10.1056/NEJMoa1501352
Erratum in :
N Engl J Med 201;373:586, Print:06-Aug-2015, Epub:16-Jul-2015, PMID:26182233, doi:10.1056/NEJMx150029

Regional, age and sex differences in baseline characteristics of patients enrolled in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS)
M. A. Bethel, J. B. Green, J.Milton, A.Tajar, S.S.Engel, R.M.Califf, R.R.Holman on behalf of the TECOS Executive Committee
Diabetes, Obesity and Metabolism 2015;17:395-402. Published:Apr-2015. Epub:13-Feb-2015. PMID:25600421. doi:10.1111/dom.12441

2013

Rationale, design, and organization of a randomized, controlled Trial Evaluating Cardiovascular Outcomes with Sitagliptin (TECOS) in patients with type 2 diabetes and established cardiovascular disease
Jennifer B. Green, M. Angelyn Bethel, Sanjoy K. Paul, Arne Ring, Keith D. Kaufman, Deborah R. Shapiro, Robert M. Califf, Rury R. Holman
American Heart Journal 2013;166:983-989.e7. Published:Dec-2013. Epub:23-Oct-2013. PMID:24268212. doi:10.1016/j.ahj.2013.09.003