The HOMA Calculator ©The University of Oxford 2013 is available without charge to clinical and non-commercial organisations, subject to the following copyright and conditions. Commercial organisations wishing to make use of this software must first make appropriate arrangements with the copyright holders (Email: email@example.com)
The University is a charitable foundation devoted to education and research, and in order to protect its assets for the benefit of those objects, the University must make it clear that no condition is made or to be implied, nor is any warranty given or to be implied, as to the accuracy of this Tool, or that it will be suitable for any particular purpose or for use under any specific conditions. Furthermore, the University disclaims all responsibility for the use which is made of the Tool. However, nothing in this statement will operate to exclude or restrict any liability which the University may have for death or personal injury resulting from negligence. It is a further condition that the software obtained from this site is not distributed further without the same conditions and copyright statements being imposed. Those seeking to incorporate any part of the HOMA Calculator into other software projects must seek the permission of the copyright holders before distribution or publication of their software.
The HOMA Calculator is intended for use by health care professionals to assist in the assessment of beta cell function and insulin sensitivity. It may be of assistance in the management of dysglycaemia or Type 2 diabetes but is not a replacement for formal medical assessment and not intended for use by patients unless in consultation with their trained medical adviser.
The standalone version of the HOMA Calculator uses the HOMA2 model to estimate beta cell function (%B) and insulin sensitivity (%S) for an individual from simultaneously measured fasting plasma glucose and fasting plasma RIA insulin values. Fasting specific insulin or C-peptide values can be used instead of RIA insulin. The HOMA2 model is calibrated to give %B and %S values of 100% in normal young subjects when using a suitable insulin assay. See Background and FAQ for further details.
The download also includes the Excel spreadhseet implementation, which incorporates the HOMA Calculator as an Excel function, estimates %B and %S values for many individuals simultaneously. A Validation spreadsheet is also included to allow verification that the library is installed and running correctly.
For older PowerPC based Macintosh machines or those using Mac OS X 10.6 or earlier: