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Background

The UKPDS Outcomes Model is based on patient data from the United Kingdom Prospective Diabetes Study. It is a computer simulation model designed to assess the total burden of disease over an extrapolated lifetime for populations with Type 2 diabetes. The UKPDS Outcomes Model uses a wide variety of input data, including knowledge of previous events for individuals, and has the ability to take into account changes in some risk factor levels over time. If these updated risk factor levels are not available the model will, by default, extrapolate the risk factor levels entered. The UKPDS Outcomes Model outputs are estimated Life Expectancy and Quality Adjusted Life Expectancy for each member of a given population.

The UKPDS Outcomes Model is a computer simulation model for estimating the long-term impact of health interventions for people with type 2 diabetes. It has been developed primarily to assess the lifetime benefits of diabetes-related interventions. In particular, it is intended to facilitate economic evaluations by estimating changes in outcomes such as life expectancy and quality adjusted life expectancy, when risk factors such as blood glucose level, blood pressure, lipid levels and smoking status are changed. It can be applied to any population with type 2 diabetes. Other potential applications include:

• Assisting health service planning for populations with diabetes
• Estimating life expectancy of people with type 2 diabetes when writing premiums for life insurance
• Calculating expected event rates for sample size calculations when designing clinical trials.

The UKPDS Outcomes Model is already being used in a range of research, clinical and commercial applications worldwide.

You can view the full UKPDS Outcomes Model Manual.

Supported platforms

The UKPDS Outcomes Model runs as an Excel spreadsheet on Windows or as a standalone application on MacOS X, Windows and Linux.

Contact Us

For all queries concerning the UKPDS Outcomes Model and its appropriate use please read the manual and the web site FAQ (www.dtu.ox.ac.uk/outcomesmodel). If your question remains unanswered, email herc@dph.ox.ac.uk
For technical enquiries concerning software installation, email outcomes.model@dtu.ox.ac.uk

News

OCDEM, Churchill Hospital, Old Road, Headington, Oxford, OX3 7LJ
Tel: +44 (0)1865 857233   Fax: +44 (0)1865 857235     Email: outcomes.model@dtu.ox.ac.uk

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