HOMA2 Calculator


The following implementations of the HOMA2 Calculator software are available:


The standalone version of the HOMA2 Calculator uses the HOMA2 model to estimate beta cell function (HOMA_%B) and insulin sensitivity (HOMA_%S) for an individual from simultaneously measured fasting plasma glucose and fasting plasma RIA insulin values. Fasting specific insulin or C-peptide values can be used instead of radioimmunoassay (RIA) insulin values. The HOMA2 model is calibrated to give HOMA_%B and HOMA_%S values of 100% in normal young subjects when using a suitable insulin assay. See Background and FAQ for further details.

Microsoft Excel

An Excel spreadsheet implementation is included with in the standard download which permits HOMA_%B and HOMA_%S estimates to be calculated for multiple individuals simultaneously. A Validation spreadsheet is also included to allow verification that the library is installed and running correctly.

Applications Programming Interface

An applications programming interface (API), encapsulating the HOMA2 Calculator as an ActiveX module or DLL on Windows or as a shared library on Macintosh, is available for incorporation in other software packages, subject to copyright as below. See the links below or Email: homa.calculator@dtu.ox.ac.uk to discuss possible licensing arrangements.

License agreements

A license is required by Commercial Organisations for use of the HOMA2 Calculator, or to incorporate into programs (Application Programming Interface-API).
A license is not required for non-commercial use of the HOMA2 Calculator Standalone and Excel implementations, only if you need the API.

The following license agreements are available to download - please check your use against the license terms. You should also read the instructions for completion:

Conditions of use and copyright

The HOMA2 Calculator ©The University of Oxford 2004-2021 is available without charge for use by clinical and non-commercial organisations. Commercial organisations wishing to make use of this software must first obtain a licence agreement.

All use of the software is subject to the following conditions: The University is a charitable foundation devoted to education and research, and in order to protect its assets for the benefit of those objects, the University must make it clear that no condition is made or to be implied, nor is any warranty given or to be implied, as to the accuracy of this Tool, or that it will be suitable for any particular purpose or for use under any specific conditions. Furthermore, the University disclaims all responsibility for the use which is made of the Tool. However, nothing in this statement will operate to exclude or restrict any liability which the University may have for death or personal injury resulting from negligence. It is a further condition that the software obtained from this site is not distributed further without the same conditions and copyright statements being imposed. Those seeking to incorporate any part of the HOMA2 Calculator into other software projects must seek the permission of the copyright holders before distribution or publication of their software.

The HOMA2 Calculator is intended for use by health care professionals to assist in the assessment of beta cell function and insulin sensitivity. It may be of assistance in the management of dysglycaemia or Type 2 diabetes but is not a replacement for formal medical assessment and not intended for use by patients unless in consultation with their trained medical adviser.


Standalone and Excel implementations

For older 32 bit or PowerPC based Macintosh machines or those using Mac OS X 10.6 or earlier: