UKPDS Outcomes Model

Estimating risk factor progression equations for the UKPDS Outcomes Model 2 (UKPDS 90)
Jose Leal, Maria Alva, Vanessa Gregory, Alison Hayes, Borislava Mihaylova, Alastair M Gray, Rury R. Holman, Philip Clarke
Diabet Med. 2021;38:e14656. Published:Oct-2021. Epub:23-Jul-2021. PMID:34297424. doi:10.1111/dme.14656

Accurately Reflecting Uncertainty When Using Patient-Level Simulation Models to Extrapolate Clinical Trial Data
Helen A. Dakin, José Leal, Andrew Briggs, Philip Clarke, Rury R. Holman, Alastair Gray
Med Decis Making. 2020;40:460-473. Published:May-2020. Epub:20-May-2020. PMID:32431211. doi:10.1177/0272989X20916442

UKPDS Outcomes Model 2: a new version of a model to simulate lifetime health outcomes of patients with type 2 diabetes mellitus using data from the 30 year United Kingdom Prospective Diabetes Study: UKPDS 82
Hayes AJ, Leal J, Gray AM, Holman RR, Clarke PM
Diabetologia 2013;56:1925-1933. Published:Sep-2013. Epub:22-Jun-2013. PMID:23793713. doi:10.1007/s00125-013-2940-y

Computer modeling of diabetes and its complications: a report on the Fourth Mount Hood Challenge Meeting
The Mount Hood 4 Modeling Group
Diabetes Care 2007;30:1638-1646. Published:Jun-2007. PMID:17526823. doi:10.2337/dc07-9919

PROactive Study
Holman RR, Retnakaran R, Farmer A, Stevens RJ
Lancet 2006;367:25-26. Published:07-Jan-2006. Epub:05-Jan-2006. PMID:16399144. doi:10.1016/S0140-6736(06)67914-2

Cost-utility analyses of intensive blood glucose and tight blood pressure control in type 2 diabetes (UKPDS 72)
Clarke PM, Gray AM, Briggs A, Stevens RJ, Matthews DR, Holman RR
Diabetologia 2005;48:868-877. Published:May-2005. Epub:15-Apr-2005. PMID:15834550. doi:10.1007/s00125-005-1717-3

A model to estimate the lifetime health outcomes of patients with type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS) Outcomes Model (UKPDS 68)
P. M. Clarke, A. M. Gray, A. Briggs, A. J. Farmer, P. Fenn, R. J. Stevens, D. R. Matthews, I. M. Stratton, R. R. Holman
Diabetologia 2004;47:1747-1759. Published:Oct-2004. Epub:27-Oct-2004. PMID:15517152. doi:10.1007/s00125-004-1527-z

The impact of diabetes-related complications on healthcare costs: results from the United Kingdom Prospective Diabetes Study (UKPDS Study No 65)
Clarke P, Gray A, Legood R, Briggs A, Holman R
Diab Med. 2003;20:442-450. Published:Jun-2003. Epub:18-Jul-2003. PMID:12786677. doi:10.1046/j.1464-5491.2003.00972.x

Estimating utility values for health states of type 2 diabetic patients using the EQ-5D
Clarke P, Gray A, Holman R
Medical Decision Making 2002;4:340-349. Published:Aug-2002. PMID:12150599. doi:10.1177/0272989X0202200412